Antibacterial Activity of Arctic Fungus, Penicillium samsonianum Against Methicillin-Resistant Staphylococcus aureus (MRSA) and Staphylococcus haemolyticus

Abstract

Antimicrobial resistance (AMR) has been a severe global health problem due to infections caused by multidrug-resistant (MDR) bacteria that are increasingly significant to mortality and morbidity. Over the years, the infections have become increasingly resistant to treatment. This situation led to an urgent exploration of novel antimicrobial compounds derived from natural sources, specifically from psychrophilic fungi, which have historically been a rich source of bioactive molecules. Arctic fungi are known for their extreme environment and unique microbial diversity. This study focuses on the microbial potential of Arctic fungi Penicillium samsonianum,which was isolated from Svalbard Island, Norway.