Effects of Antihypertensive Drugs on Alveolar Bone Loss in Patients with Chronic Periodontitis: A Retrospective Study

Authors

  • FH Al-Bayaty Center of Periodontology Studies, Faculty of Dentistry, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia
  • OE Ibrahim Center of Preclinical Science Studies, Faculty of Dentistry, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia
  • C William Faculty of Dentistry, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia
  • NA Khairuddin Faculty of Dentistry, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia

DOI:

https://doi.org/10.24191/cos.v5i0.17505

Keywords:

alveolar bone loss, antihypertensive drugs, chronic periodontitis

Abstract

Objective: This retrospective study aims to evaluate the possible effects of antihypertensive drugs on alveolar bone loss in patients with chronic periodontitis. Methods: 50 patients on antihypertensive drugs selected as the experimental group and 50 patients with chronic periodontitis with no known systemic illnesses as control group were randomly selected as the study samples. Orthopantomographs were obtained, calibration and assessment of alveolar bone loss was performed by using the computer software program available in the faculty, through radiographic linear measurement procedure. Premolars, first and second molars of both maxilla and mandible were measured from the most apical point to the cementoenamel junction for mesial and distal aspects in the form of millimetres and percentile of the root length. Data was statistically analyzed using independent t-test and Analysis of Covariance in SPSS Version 23 with significance at P-value, p<0.05. Results: A total of 2428 sites were measured. Analysis has shown that there is significant difference in alveolar bone loss in experimental group and control group (p=0.002). Bone loss in the experimental group was less (16.28 ± 9.48) compared to the control group (22.66 ± 12.58). Within the experimental group, there was no significant difference for the duration of antihypertensive drug intake. However, the bone loss was more among the males (19.71 ± 11.22) than the females (12.99 ± 5.99). Conclusion: Antihypertensive drugs appear to have a positive effect on alveolar bone loss progression. Patients under these drugs exhibit lower levels of bone loss compared to those who are not.

Compendium of Oral Science Cover 2018

Downloads

Published

2018-09-01

How to Cite

Al-Bayaty, F., Ibrahim, O., William, C., & Khairuddin, N. (2018). Effects of Antihypertensive Drugs on Alveolar Bone Loss in Patients with Chronic Periodontitis: A Retrospective Study. Compendium of Oral Science, 5, 26–36. https://doi.org/10.24191/cos.v5i0.17505

Issue

Vol. 5 (2018): Compendium of Oral Science

Section

Original Article

License

Copyright (c) 2024 Compendium of Oral Science

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Materials contained in the journal may be reproduced for educational purposes provided that both the author(s) and the journal are appropriately recognised; otherwise duplication is not permitted. No articles, reports, or portions there of may be translated into other languages, published in books, journals, magazines, or any other print form without written permission from the authors and from the journal.

Disclaimer: The statements, opinions and data expressed in the articles and reports herein are those of the author(s) and not of the publisher and the editor(s). The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any schemes, methods, instructions or ideas referred to in the content.