Nano Silver Fluoride Preparation as an Anti-Caries Agent: A Scoping Review

Authors

  • Nadhirah Sakinah Rosman Faculty of Dentistry , Universiti Sains Islam Malaysia image/svg+xml
  • Annapurny Venkiteswaran Centre of Paediatric Dentistry and Orthodontic Studies, Faculty of Dentistry , MARA University of Technology image/svg+xml
  • Alaa Sabah Hussein Centre of Paediatric Dentistry and Orthodontic Studies, Faculty of Dentistry , MARA University of Technology image/svg+xml

DOI:

https://doi.org/10.24191/cos.v13i1.7296

Keywords:

nano silver fluoride, silver nanoparticles, anticaries agent, nanomaterial synthesis, topical fluoride

Abstract

This scoping review aims to explore existing literature on the synthesis of Nano Silver Fluoride (NSF) and to identify the key variables that may influence its effectiveness as an anti-caries agent. Following the Joanna Briggs Institute (JBI) methodology, a scoping review was conducted to examine the available studies related to NSF formulation for dental caries prevention. A systematic search across academic databases was performed. Studies were included if they described methods for preparing NSF intended for anti-caries use. A total of 704 articles were initially identified. After screening and eligibility assessment, nine studies were included in the final review. These studies varied in terms of population, study design, and evaluation methods. NSF was primarily synthesized through chemical methods using various silver precursors, reducing agents, and stabilizers. The resulting nanoparticles were all spherical, with sizes ranging from 3.2 to 16 nm. NSF concentrations ranged from 400 to 33,989 ppm. Despite methodological differences, all studies supported the anti-caries potential of NSF. NSF is a promising, non-invasive agent for caries prevention in both children and adults. Its effectiveness is supported across different synthesis methods, provided the presence and stability of NSF are verified.

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Published

2026-03-01

How to Cite

Rosman, N. S., Venkiteswaran, A., & Hussein, A. S. (2026). Nano Silver Fluoride Preparation as an Anti-Caries Agent: A Scoping Review. Compendium of Oral Science, 13(1). https://doi.org/10.24191/cos.v13i1.7296