Antarctic Biota’s Hidden Value: A Narrative Review of Antarctic Biota as Potential Neuroprotection Therapy

Abstract

The interest in researching neuroprotection activity in the Antarctic has recently increased, despite the paucity of studies in this field. The low temperatures in Antarctica are recognized as extreme conditions, which limits research in the region. This, this review aims to examine the potential neuroprotective qualities of the Antarctic biota. Extreme and isolated, Antarctica dwells on a wide variety of biota that have evolved specifically to withstand the harsh conditions there. Recent research has revealed the potential neuroprotective properties of various Antarctic native organisms. This region's microbes, plants and marine animals have developed complex metabolic pathways and compounds with neuroprotective qualities. These compounds can reduce damage to neurons, improve cellular resiliency and alter important pathways implicated in neurodegenerative diseases.