Determinig the Effects of Sulphide Derivatives on the Efficacy of Clindamycin against Staphylococcus aureus

Abstract

Staphylococcus aureus is a significant human pathogen that has the potential to cause a variety of severe infections, particularly in the context of antibiotic resistance. The community nowadays, mostly relying on modern drugs manufactured to treat infection such as clindamycin, and others. However, antimicrobial resistance has become a major issue for public health. Recent studies reported that the reactive sulphur species (RSS) potentially cause the decrease of antimicrobial potency towards several bacteria. The use of RSS derivatives such as glutathione in skin care products has been commonly applied.