Profiling on Metabolites in Human Milk of Mothers with Self-Claimed Respiratory Allergy Using Nuclear Magnetic Resonance

Abstract

Chronic inflammatory respiratory disease, asthma is typified by recurrent episodes of dyspnoea, coughing, and wheezing. Asthma impact 8% to 13% of pregnant women globally and its rate is merely climbing. In recent years, there has been a lot of discussion about the potential link between human milk and the development of allergy disorders. Metabolomics is a new approach that provides for a thorough understanding of the alterations in metabolites and the consequent signalling pathways. This study comprises the profiling metabolites in human milk based on maternal self-claimed respiratory allergy. The objective of this study is to profile the metabolites of human milk based on maternal respiratory allergy and to identify the difference between human metabolites of healthy mother (control group) and mothers with respiratory allergy (intervention group).