Comparative Analysis of Anti - Inflammatory Capabilities of Combined Astaxanthin and Tocotrienols in CALU-3 and RAW264.7

Abstract

Chronic inflammation is a major contributor to numerous diseases, such as cancer, neurological disorders and cardiovascular diseases. It has been proved that astaxanthin and tocotrienols are two naturally occurring compounds with anti-inflammatory and antioxidant properties that inhibit inflammatory responses and reduce oxidative stress. If there is a reduced in inflammation in cells, it indicates that the combination of both inflammatory agents effectively reduces inflammation. This study used CALU-3 and RAW264.7 cells were used to evaluate the anti-inflammatory effects of astaxanthin and tocotrienols. This study aims to investigate the effects of combined astaxanthin and tocotrienols on the inflammatory responses of CALU-3 human lung cells and RAW264.7 murine macrophage cells.