Molecular docking study of compounds from Dryobalanops aromatica as the anti-MRSA agent

Authors

  • Nur Shasha Iwani Mohd Isaa School of Biology, Faculty of Applied Sciences, University Teknologi MARA, Shah Alam, Malaysia
  • Latifah Munirah Bakar School of Biology, Faculty of Applied Sciences, University Teknologi MARA, Shah Alam, Malaysia
  • Mohamad Zakkirun Abdullah Department of Fundamentals in Dental and Medical Science, Kulliyyah of Dentistry, International Islamic University Malaysia

Keywords:

Antibiotic resistance, Methicillin-resistant Staphylococcus aureus (MRSA), Drayobalanops aromatica, Anti-MRSA agents, Molecular docking studies

Abstract

The emergence of antibiotic-resistant microorganisms poses a significant global health threat, particularly Methicillin-resistant Staphylococcus aureus (MRSA), which resists several antibiotics, including oxacillin, amoxicillin, and penicillin. Despite advancements in antimicrobial drugs, resistance continues to rise, necessitating alternative treatments. This study investigates the potential of compounds from Drayobalanops aromatica as anti-MRSA agents using molecular docking techniques. D. aromatica, known for its valuable timber and non-timber products like camphor, is indigenous to Southeast Asia. It has been historically used for its medicinal properties, making it a promising candidate for new antibacterial compounds.

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Published

15-05-2025

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Section

Articles