Antibacterial Activity of Nigella sativa (Black Seed) Oil towards Bacillus cereus and Escherichia coli

Authors

  • Farah An-Nisa Mohd Kassim School of Biology, Faculty of Applied Sciences, University Teknologi MARA, Shah Alam, Malaysia
  • Latifah Munirah Bakar School of Biology, Faculty of Applied Sciences, University Teknologi MARA, Shah Alam, Malaysia

Keywords:

Nigella sativa oil, gastrointestinal infections, disk diffusion, minimum inhibitory concentration, percentage inhibition of diameter growth

Abstract

Gastrointestinal infections caused by Bacillus cereus and Escherichia coli pose a threat to human health. The antibacterial resistance in both strains makes it difficult to treat these infections effectively. Nigella sativa has been used for centuries for its medicinal properties as it contains thymoquinone; a compound known to exhibit anti-inflammatory, antimicrobial, and anticancer activities. This study aims to investigate the antibacterial properties of N. sativa oil against B. cereus and E. coli, determine the minimum inhibitory concentration (MIC) and the percentage inhibition of diameter growth (PIDG) value.

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Published

15-05-2025

Issue

Vol. 45 (2025): CAS 2024

Section

Articles