Antimicrobial activity of Syzygium aromaticum extract loaded on Oral Thin Film against Streptococcus mutans
Keywords:
Syzygium aromaticum, Streptococcus mutans, Oral Thin Film, dental caries, antimicrobial effectAbstract
S. aromaticum or clove, consists of various biological compounds that contribute to its diverse biological activities. Products in the market that are used to treat dental caries have some limitations as the designs are inconvenient. For example, capsules are hard to swallow, while gel products are easily washed away by saliva. Thus, Oral Thin Film (OTF) is an effective option. This study aims to investigate the antimicrobial properties of S. aromaticum against S. mutans. The next objective is to formulate an ideal thickness of OTF containing S. aromaticum extract. Lastly, to determine the extended-release properties of S. aromaticum extract containing film.