Analysis of Malathion in Human Blood Utilizing Solid-Phase Extraction (SPE) Coupled With Gas Chromatography-Mass Spectrometry (GC-MS)

Abstract

Malathion, a widely used organophosphorus pesticide in agriculture, can be detected and quantified in blood samples, which is crucial for investigating suspected poisoning, accidental exposure, or intentional harm cases. With an LD50 classified as dangerous, researchers have been investigating its impact to minimize usage and raise awareness. Various extraction methods, such as liquid-liquid extraction (LLE), have been used, but they can be time-consuming and require large amounts of samples and solvents, resulting in high costs.