Effect of Amoxicillin Biodegradation by Fungus Aspergillus tamarii and its Antimicrobial Activity

Abstract

Amoxicillin biodegradation refers to the process by which microorganisms, such as fungi, break down the antibiotic amoxicillin into simpler, less harmful compounds. Amoxicillin is extensively used across multiple fields, including human medicine, agriculture, and aquaculture, due to its broad-spectrum antibacterial properties. However, the pervasive use of this antibiotic has led to significant ecological contamination and the development of antibiotic resistance, primarily due to the release of unmetabolized amoxicillin and its byproducts into aquatic environments. This contamination poses a threat to microbial ecosystems and necessitates effective biodegradation strategies.