Histopathological Analysis of Vaginal Structure in Rats Following Honey Supplementation

Abstract

The vagina, a crucial organ linked to reproductive systems, puberty, period cycle, and menopause, undergoes changes due to aging and hypoestrogenism. This can result from factors such as aging, cancer treatment, ovarian failure, or surgical menopause. Honey, a popular global health food, contains numerous nutrients and antioxidants. It has been shown to prevent uterine and vaginal shrinkage and dryness in menopausal animals, possibly due to its high levels of phytoestrogens. Gelam Honey, a Malaysian monofloral wild honey produced by Apis dorsata bees, has therapeutic properties such as antioxidant, anti-inflammatory, anti-cancer, and accelerated wound healing. This study aims to observe the tissue of normal rats given varying doses of honey.