Elucidating the potential mechanism of kaempferol and quercetin in ameliorating cognitive impairment using computational analysis

Abstract

This study explores the neuroprotective properties of two flavonoids, kaempferol and quercetin, in alleviating cognitive impairment, which has become a public health concern due to the aging population. The researchers used in silico network pharmacology and molecular docking techniques to uncover the potential mechanisms of these compounds. Comprehensive interaction networks were constructed to integrate data from various databases related to protein-protein interactions, drug-target interactions, and disease-gene associations