Assessing The Quality of Voren®, Remafen® and Remethan® Medicinal Tablets Sold in Malaysian Market

Abstract

Voren®, Remafen® and Remethan® medicinal tablets are the common brands sold in the local pharmacies that consist of diclofenacsodium as the active ingredient. These products are used to reduce pain from joint and muscles problem usually associates with arthritis. Assessing the quality of these products are very crucial due to the life threatening to overdose patients with cardiovasculardiseases and Asian countries reported to have the most counterfeit drugs. There are various ways to assess the quality of drugs but inthis study the quality of the drug is assessed based on diclofenac sodium content per tablet and its percent assay. The peak area of diclofenac sodium is measured using high performance liquid chromatography (HPLC). The quantification was based on external standard calibration curve, where there is linear relationship between the peak area of the analyte with its corresponding prepared concentration.