Antimicrobial Potential of Pd(II) complexes bearing 1,1'-Bis(diphenylphosphino)ferrocene (dppf) Moiety

Abstract

Antimicrobial resistance (AMR) threatens worldwide health, including Malaysia. Health Minister Datuk Seri Dr. Dzulkefly Ahmad predicted 87,000 AMR deaths from 2020 to 2030 without appropriate treatments. AMR must be addressed to maintain public health and economic stability. Pd(II) complexes exhibit structural adaptability that enables them to disrupt microbial functions, mimic essential metal ions, and induce oxidative stress, positioning them as promising candidates for addressing resistant infections. This research evaluates the efficacy of Pd(II) complexes with dppf ligand against human pathogenic microorganisms.