Synthesis of 6-Hydroxycoumarin Derivatives

Abstract

Coumarin, Dipteryx Odorata Willd known as Tonka Bean, is the naturally occurring compound. The compound also distributed from nature such as found in roots, flowers and fruits in the presence of secondary metabolites. The group of coumarin consists of simple coumarins, furanocoumarins, dihydrofurano coumarins, phenyl coumarins etc. Existence studies mentioned the functionality of coumarins in toxicological, biological and pharmacological properties. However, the derivatives of hydroxycoumarin, a hydroxylated simple coumarin groups having different type of synthesis methods that not proven the characterization of the compounds. The study utilized the synthesis methodology for the 6-hydroxycoumarin derivatives as outcomes of the recent
characteristic evidence of the compound. As the purpose of this study able to establish the recent research of the 6-hydroxycoumarin derivatives.