SCREENING FOR PHYTOCHEMICAL CONSTITUENTS AND ANTIOXIDANT ACTIVITY OF FLOWER EXTRACTS OF QUISQUALIS INDICA LINN

Authors

  • Suhaidi Ariffin School of Chemistry and Environment, Faculty of Applied Sciences Universiti Teknologi MARA (UiTM), Cawangan Negeri Sembilan, Kampus Kuala Pilah, 72000 Kuala Pilah, Negeri Sembilan, Malaysia
  • Nurul Izzah Radin Mokthar School of Chemistry and Environment, Faculty of Applied Sciences Universiti Teknologi MARA (UiTM), Cawangan Negeri Sembilan, Kampus Kuala Pilah, 72000 Kuala Pilah, Negeri Sembilan, Malaysia

Keywords:

Quisqualis indica L., phytochemical, antioxidant, DPPH

Abstract

Rangoon creeper, scientifically known as Quisqualis indica Linn. belongs to the family of Combretaceae and has been used as a traditional medicine for a long time. This plant treats many illnesses, such as fever and boil, and relieves headaches. However, the scientific data to support the effectiveness of this plant as a medicinal source still needs to be discovered. Therefore, this study aims to identify phytochemical constituents and determine the antioxidant properties of flower extracts of Q. indica L. Maceration technique was employed to extract the sample using three different solvent polarities: n-hexane, ethyl acetate, and methanol. The extractive yield of methanol showed the highest percentage, 17.41%, followed by ethyl acetate (3.19%) and n-hexane (1.45%), respectively. For phytochemicals screening, all extracts exhibited the presence of alkaloids, flavonoids, saponins, terpenoids, and tannins, except the n-hexane extract, where flavonoids are not detected. The antioxidant assay was done by DPPH (2,2 diphenyl-1-picrylhydrazyl) assay at 1000 µg/mL concentration. It was found that the methanol extract gave the highest DPPH radical scavenging activity of 99.11 ± 0.50%, which is higher than the ascorbic acid standard used. The results justify its use as a medicinal plant. This local species has a higher potential as an antioxidant agent as well.

References

Afify, A. E. M. M. R., & Hassan, H. M. M. (2016). Free radical scavenging activity of three different flowers-Hibiscus rosa-sinensis, Quisqualis indica and Senna surattensis. Asian Pacific Journal of Tropical Biomedicine, 6(9), 771-777.

Anusha, P., & Bai, R. S. (2017). Phytochemical profile and antimicrobial potential of methanolic extracts of bark and leaf of Quassia indica (Gaertn.) Nooteb. The Journal of Phytopharmacology, 6(5), 269–276.

Barik, B. S., Das, S., & Hussain, T. (2020). Pharmacognostic properties of Quisqualis indica Linn: Against human pathogenic microorganisms: An insight review. European Journal of Medicinal Plants, 31(20), 87-103.

Dutta, A., Biswas, S., Biswas, M., & Ghosh, P. (2019). Stem and flower of Rangoon creeper: a comparative study Phytochemical screening, anti-oxidant and anti-microbial activity of leaf, stem and flower of Rangoon creeper: a comparative study. Journal of Medicinal Plant Studies, 7(2), 123–130.

Ekor, M. (2014). The growing use of herbal medicines: Issues relating to adverse reactions and challenges in monitoring safety. Frontiers in Neurology, 4(177), 1–17.

Jani, N. A., Azizi, N. A. A., & Aminudin, N. I. (2020). Phytochemical screening and antioxidant activity of Psidium guajava. Malaysian Journal of Analytical Sciences, 24(2), 173–178.

Kibria, A. A., & Kar, A. (2019). Extraction and evaluation of phytochemicals from banana peels (Musa sapientum) and banana plants (Musa paradisiaca). Malaysian Journal of Halal Research Journal, 2(1), 22–26.

Mukherjee, D., & Chandra, G. (2017). Flower extracts of Quisqualis indica as novel antibacterial agents against some pathogenic bacteria. Annals of Pharmacology and Pharmaceutics, 2(1), 1-2.

Rashid, H. O., Akter, M. M., Uddin, J., Islam, S., & Rahman, M. (2023). Antioxidant, cytotoxic, antibacterial, and thrombolytic activities of Centella asiatica L.: possible role of phenolics and flavonoids. Clinical Phytoscience, 9(1), 1–9.

Roghini, R., & Vijayalakshmi, K. (2018). Phytochemical screening, quantitative analysis of flavonoids and minerals in ethanolic extract of Citrus paradisi. International Journal of Pharmaceutical Sciences and Research, 9(11), 4859.

Sahu, J., Patel, P. K., & Dubey, B. (2012). Quisqualis indica Linn: A Review of its Medicinal Properties. International Journal of Pharmaceutical & Phytopharmacological Research, 1(5), 313–321.

Shah, A., Khan, Z. ud D., Saleem, S., & Farid, S. (2019). Antioxidant activity of an ethnobotanically important plant, Quisqualis indica Linn. Pakistan Journal of Pharmaceutical Sciences, 32(1), 95-102.

Shaikh, J. R., & Patil, M. (2020). Qualitative tests for preliminary phytochemical screening: An overview. International Journal of Chemical Studies, 8(2), 603–608.

Singh, S., Rai, A., Maity, S., Sarkar, S., Maji, S., & Saha, S. (2017). Effect of ethanolic extract of Quisqualis indica L. flower on experimental esophagitis in albino Wistar rats. Indian Journal of Experimental Biology, 55(2), 122–126.

Sutar, S. B., Kadam, S. S., Patil, S. B., Patil, S. S., & Mahajan, R. K. (2020). The phytochemical investigation, anthelmintic and antioxidant activities of Quisqualis. Pharmaceutical Resonance, 3(1), 15–21.

Yang, L., Wen, K. S., Ruan, X., Zhao, Y. X., Wei, F., & Wang, Q. (2018). Response of plant secondary metabolites to environmental factors. Molecules, 23(4), 1-26.

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Published

2024-10-31

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