Unlocking the Power of Calcium Sulfate: Paving the Way for Periodontal Regeneration Across Time

Abstract

Various type of bone substitutes was introduced including autograft,

allograft, and xenograft to replace the missing bone. However, each has

its drawbacks which prompts the use of other alternatives such as

alloplastic materials. Calcium sulfate (CS) is one of the oldest alloplastic

materials that has a long history in regenerative medicine. This narrative

review aimed to address several key questions: 1) Which regenerative

material is preferable for use; xenograft or alloplastic material? 2) What

is the versatility of calcium sulfate in periodontal regeneration? 3) How

can calcium sulfate and stem cell technology shape the future of

periodontal regeneration?